Jun 13, 2016 · Scientists confirm reprogrammed adult stem cells identical to embryonic stem cells. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another a more specialized cell type, such as a muscle cell, a red blood cell, or a brain cell (Fig 1). Scientists distinguish several types of stem cells.Author: Science X Staff. Feb 15, 2014 · Direct reprogramming of adult cells: avoiding the pluripotent state Abstract. The procedure of using mature, fully differentiated cells and inducing them toward other Changing the cell fate. The traditional view of cell differentiation initially involved Regenerative medicine, stem cells, Cited by: 70.
In order to turn adult cells back into pluripotent or embryonic-like stem cells, scientists use viruses to insert four genes – Sox2, Oct4, Klf4, and cMyc – into the cells. These reprogrammed cells, called induced pluripotent stem cells (iPS cells), have generated a huge amount of excitement in the field. Masaki et al. discover that leprosy bacteria are able to hijack the plasticity of differentiated adult Schwann cells to reprogram them into a stem cell-like state. These reprogrammed cells spread infection to secondary tissues by direct differentiation and Cited by: 152.
In late 2007, a technique was proven in principle that can reprogram adult stem cells so that they have many of the same properties and potential of embryonic stem cells. This may completely revolutionize future research techniques, allow government research funding to be increased, and offer hope to the approximately 100 million Americans who suffer from a wide range of debilitating diseases and disorders that may eventually be treated or cured with stem cells. Feb 22, 2018 · Discovery could speed clinical translation of stem cell therapies. A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells.